Navigate target safety with augmented intelligence

Comprehensive safety reporting for any drug target

Screenshot of Sable Target Intelligence for a target highlighting the overall safety score, potential risk areas and highlighted phenotypes of interest.

Navigate target safety with augmented intelligence

Comprehensive safety reporting for any drug target

Screenshot of Sable Target Intelligence for a target highlighting the overall safety score, potential risk areas and highlighted phenotypes of interest.

Navigate target safety with augmented intelligence

Comprehensive safety reporting for any drug target

Screenshot of Sable Target Intelligence for a target highlighting the overall safety score, potential risk areas and highlighted phenotypes of interest.

The Problem

Compiling relevant target safety information is often difficult and time-consuming

Compiling relevant target safety information is often difficult and time-consuming

Slower

Slower

Manual assessments require time and expertise of multiple individuals.

Manual assessments require time and expertise of multiple individuals.

Incomplete

Incomplete

The volume of data makes it difficult to complete a systematic analysis.

The volume of data makes it difficult to complete a systematic analysis.

Superseded

Superseded

Information falls out of date over the course of a drug development project.

Information falls out of date over the course of a drug development project.

The SOLUTION

Sable Bio offers Comprehensive Target Safety Intelligence in one place

Sable Bio offers Comprehensive Target Safety Intelligence in one place

Put recommended mitigations in place and reduce the chances of safety issues with a platform specially designed for drug target safety

Put recommended mitigations in place and reduce the chances of safety issues with a platform specially designed for drug target safety

Comprehensive

Reports respond to your chosen modality and mode of action.

Comprehensive

Reports respond to your chosen modality and mode of action.

Comprehensive

Reports respond to your chosen modality and mode of action.

Versatile

Reports respond to your chosen modality and mode of action.

Versatile

Reports respond to your chosen modality and mode of action.

Versatile

Reports respond to your chosen modality and mode of action.

Safety Specific

Digest relevant risks without getting lost in endless data.

Safety Specific

Digest relevant risks without getting lost in endless data.

Safety Specific

Digest relevant risks without getting lost in endless data.

Fresh

Return to fresh data and highlighted changes.

Fresh

Return to fresh data and highlighted changes.

Fresh

Return to fresh data and highlighted changes.

Drug Discovery Use Cases

Drug Discovery Use Cases

Individual Target Safety Assessment

Evaluate possible safety risks associated with a selected target.

Tailored to your chosen modality and mode of action.

Follow recommendations to reduce the chances of safety failures in the clinic.

Individual Target Safety Assessment

Evaluate possible safety risks associated with a selected target.

Tailored to your chosen modality and mode of action.

Follow recommendations to reduce the chances of safety failures in the clinic.

Individual Target Safety Assessment

Evaluate possible safety risks associated with a selected target.

Tailored to your chosen modality and mode of action.

Follow recommendations to reduce the chances of safety failures in the clinic.

Target Selection

Rank a set of targets for safety risks associated with your chosen modality.

Evaluate targets against a series of safety related risk categories

Explore and select the targets least likely to bring safety concerns.

Target Selection

Rank a set of targets for safety risks associated with your chosen modality.

Evaluate targets against a series of safety related risk categories

Explore and select the targets least likely to bring safety concerns.

Target Selection

Rank a set of targets for safety risks associated with your chosen modality.

Evaluate targets against a series of safety related risk categories

Explore and select the targets least likely to bring safety concerns.

Comprehensive Safety Coverage

Comprehensive Safety Coverage

Comprehensive Safety Coverage

• Customised ontologies specially focused on toxicology

• Customised ontologies specially focused on toxicology

• Customised ontologies specially focused on toxicology

• Compatible integration across data sources, including directionality of effect

• Compatible integration across data sources, including directionality of effect

• Compatible integration across data sources, including directionality of effect

• AI-augmented information extraction and curation

• AI-augmented information extraction and curation

• AI-augmented information extraction and curation

Quantified Safety Assessments

Quantified Safety Assessments

Quantified Safety Assessments

• Quantified and interpretable probability scores

• Quantified and interpretable probability scores

• Quantified and interpretable probability scores

• Directionality, expression level and other context accounted for

• Directionality, expression level and other context accounted for

• Directionality, expression level and other context accounted for

• Benchmarked on real-world safety events

• Benchmarked on real-world safety events

• Benchmarked on real-world safety events

Recommended Actions

Recommended Actions

Recommended Actions

• Safety risks are accompanied by suggested actions and mitigations

• Safety risks are accompanied by suggested actions and mitigations

• Safety risks are accompanied by suggested actions and mitigations

• Mitigations include assays and other experimental validations to reduce later stage risks

• Mitigations include assays and other experimental validations to reduce later stage risks

• Mitigations include assays and other experimental validations to reduce later stage risks

Works on less-studied targets

Works on less-studied targets

Works on less-studied targets

• Expansions by mechanism, target similarity, or potential off-target effects

• Expansions by mechanism, target similarity, or potential off-target effects

• Expansions by mechanism, target similarity, or potential off-target effects

• Built-in measures to avoid bias towards well-studied subjects

• Built-in measures to avoid bias towards well-studied subjects

• Built-in measures to avoid bias towards well-studied subjects

Fits your organisation

Fits your organisation

Flexible to your stage

Flexible to your stage

Configure reports with experimental data if you have it, or set up manually for earlier ideas.

Configure reports with experimental data if you have it, or set up manually for earlier ideas.

Bring your data

Bring your data

Bring your data

Securely add your own experimental, clinical or text data for proprietary insights.

Securely add your own experimental, clinical or text data for proprietary insights.

API Access

API Access

API Access

We offer convenient programmatic access to reports and scores for data-driven teams.

We offer convenient programmatic access to reports and scores for data-driven teams.

Book a demo with us today

Book a Demo

Book a demo with us today

Book a Demo

Book a demo with us today

Book a Demo