2 Sept 2024
Our Target Safety Assessments offer a systematic, quantified approach to help users understand risks and plan appropriate mitigations. Assessing target safety at an early stage is crucial: users need to understand the mechanisms and phenotypes that could lead to adverse reactions and regulatory setbacks in later stages. This guides the de-risking assay roadmap, to ensure that only safer drug targets advance through the development pipeline.
An effective target safety assessment helps scientists synthesise a broad range of key evidence types, including relevant clinical studies, genetic and experimental evidence alongside multiple forms of literature-derived information. It summarises evidence directly or indirectly related to the target.
Additional safety information comes from the nature of the target itself, as well as the expected direction of modulation .
The Sable Difference
While traditional Target Safety Assessment services offer manually-curated reports compiled from public data, we believe in a more dynamic approach:
Live Documents: Our reports automatically update as new scientific data and literature emerge, ensuring you always have the most current safety insights at your fingertips.
Advanced Data Pipelines: Our pipelines map key safety-relevant relationships from clinical results, genetic experiments and scientific literature, providing a multi-modal data advantage.
Precision and Systemization: Our techniques resolve directionality of effect and quantify safety signals, allowing key risks to be recognised and prioritised.
Sable offers these insights in a live platform, allowing immediate access to your selected targets. Your subscription includes access to continually updated data and cutting-edge performance in predictive toxicology.
Features of Sable Target Assessments
Comprehensive: Covers relevant clinical, genetic, textual, and experimental data.
Safety-Specific: Focused on identifying and mitigating safety risks
Always Fresh: Regularly refreshed with the latest data and predictive insights.
Navigate your drug development journey with confidence using SableBio’s Target Safety Assessments. If you'd like to get in touch, please click here.
